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骨干:曹双河 - 中国农业科学院作物科学研究所


 



姓  名:曹双河   性 别:男
职  称:副研究员
联系电话:010-82108610
电子邮箱:caoshuanghe@caas.cn
个人网页:
课 题 组:小麦品质育种
 

个人简介:

曹双河,副研究员,中国农业科学院科技创新工程小麦亲本创制与新品种选育团队骨干成员。1992年9月至1999年7月在河南农业大学攻读学士和硕士学位,1999年9月至2002年6月在中国农业大学攻读博士学位。2002年7月至2007年7月在中国科学院遗传与发育生物学研究所任助理研究员,2007年8月至2008年1月在美国加州大学戴维斯分校做访问学者,2008年2月至2012年12月在俄克拉荷马州立大学和俄克拉荷马大学从事博士后研究,2013年1月至2014年6月在中国科学院遗传与发育研究所做客座,2014年7月在中国农业科学院作物科学研究所工作至今。

研究方向:

小麦分子遗传育种。

主要贡献:

挖掘鉴定了多个新型高分子量麦谷蛋白亚基基因;建立了小麦广谱抗性基因Lr34、千粒重基因TaTGW6-A1和TaTPP-6AL1、抽穗期控制基因TaELF3-1DL及重要矮秆基因Rht24的分子标记辅助选择体系;构建了小麦和二穗短柄草高通量酵母双杂筛选体系,并据此拓展了小麦春化诱导开花的调控网络;通过定点突变及EMSA、ChIP、3C等分子互作技术揭示了光周期开花途径中NF-Y和CO协同调控开花素的分子机理。

获奖成果和荣誉称号:

2015年入选中国农业科学院“青年英才”;2015年“CIMMYT小麦引进、研究与创新利用”获国家科技进步二等奖;2017年“高产节水多抗广适冬小麦品种中麦175的选育与应用” 获得神农中华农业科技奖一等奖。

在研科研项目:

1. 主持国家自然科学基金(31571663):小麦高分子量麦谷蛋白亚基基因的转录调控解析
2. 负责北京市科技计划重大项目子课题1(D151100004415003-1):小麦分子育种平台建设和分子标记技术研究
3. 负责转基因生物新品种培育重大专项任务4(2016ZX08009003-4):小麦和玉米品质基因克隆与功能验证
4. 参加十三五重点研发项目(2016YFD0100500):主要农作物品质性状形成的分子基础

主要论文和著作:

1. X Tian, W Wen, L Xie, L Fu, D Xu, C Fu, D Wang, X Chen, X Xia, Q Chen, Z He*, S Cao*. (2017) Molecular mapping of reduced plant height gene Rht24 in bread wheat. Frontiers in Plant Science 8:1379
2. P Zhang, Z He, X Tian, F Gao, D Xu, J Liu, W Wen, L Fu, G Li, X Sui, X Xia, C Wang*, Cao S*. (2017) Cloning of TaTPP-6AL1 associated with grain weight in bread wheat and development of functional marker. Molecular Breeding 37:78
3. Y Dong, J Liu, Y Zhang, H Geng, A Rasheed, Y Xiao, S Cao, L Fu, J Yan, W Wen, Y Zhang, R Jing, X Xia, Z He*. (2017) Genome-wide association of stem water soluble carbohydrates in bread wheat. PLoS ONE 11(11): e0164293
4. J Wang, W Wen, M Hanif, X Xia, H Wang, S Liu, J Liu, L Yang, S Cao*, Z He*. (2016) TaELF3-1DL, a homolog of ELF3, is associated with heading date in bread wheat. Molecular Breeding 36:161
5. M Hanif, F Gao, J Liu, W Wen, Y Zhang, A Rasheed, X Xia, Z He*, S Cao*. (2016) TaTGW6-A1, an ortholog of rice TGW6, is associated with grain weight and yield in bread wheat. Molecular Breeding 36:1
6. S Subburaj, S Cao, X Xia, Z He*. (2016) Phylogenetic analysis, lineage-specific expansion and functional divergence of seed dormancy 4-like genes in plants. PLoS ONE 11(6): e0153717
7. S Cao, Z Li, C Gong, H Xu, Y Ran, S Hao, X Wang, D Wang, X Zhang*. (2014) Identification and characterization of high-molecular-weight glutenin subunits from Agropyron intermedium. PloS ONE 9: e87477
8. S Cao, R Kumimoto, N Gnesutta,A Calogero,R Mantovani,BF Holt III*. (2014)A distal CCAAT/NUCLEAR FACTOR Y complex promotes chromatin looping at the FLOWERING LOCUS T promoter and regulates the timing of flowering in Arabidopsis. Plant Cell 26: 1009–1017
9. S Niu*, Y Luo, D Li, S Cao, J Xia, J Li, MD Smith. (2014) Plant growth and mortality under climatic extremes: an overview. Environmental and Experimental Botany 98:13-19
10. C Gong, S Cao, R Fan, B Wei, G Chen, X Wang, Y Li, X Zhang*. (2013) Identification and phylogenetic analysis of a CC-NBS-LRR encoding gene assigned on chromosome 7B of wheat. International Journal of Molecular Sciences 14: 15330-15347
11. G Li, M Yu, T Fang, S Cao, BF. Carver, L Yan*. (2013) Vernalization requirement duration in winter wheat is controlled by TaVRN-A1 at the protein level. Plant Journal 76: 742-753
12. S Cao*, L Yan. (2013) Construction of a high-quality wheat yeast two-hybrid (Y2H) library and its application to vernaliztion key regulator TaVrnA1. BMC Research Note 6: 81
13. S Cao, RW Kumimoto, CL Siriwardana, JR Risinger, BF Holt III*. (2011) Identification and characterization of NF-Y transcription factor families in the monocot model plant Brachypodium distachyon. PLoS ONE 6: e21805
14. S Cao, CL Siriwardana, RW Kumimoto, BF Holt III*. (2011) Construction of high quality GatewayTM entry libraries and their application to yeast two-hybrid for the monocot model plant Brachypodium distachyon. BMC Biotechnology 11: 53
15. S Cao, BF Carver, X Zhu, T Fang, Y Chen, RM Hunger, L Yan*. (2010) A Single-nucleotide polymorphism that accounts for allelic variation in the Lr34 gene and leaf rust reaction in hard winter wheat. Theoretical and Applied Genetics 121: 385-392
16. S Cao, H Xu, Z Li, X Wang, D Wang, A Zhang, X Jia and X Zhang*. (2007) Identification and characterization of a novel Ag. Intermedium HMW-GS gene from T. aestivum-Ag. Intermedium addition lines TAI-I series. Journal of Cereal Science 45: 293-301
17. S Cao, X Zhang, A Zhang*. (2005) Review of the molecular mechanism and genetics of photoperiod and/or temperature sensitive genic male sterility. Chinese Bulletin of Botany 22: 19-26
18. S Cao, P Wan, X Zhang*. (2004) Isolation and characterization of an Mla-like gene of wheat. Acta Botanica Sinica (JIPB) 46: 744-750
19. S Cao,X Guo,D Liu,X Zhang,A Zhang*. (2004) Preliminary gene-mapping of photoperiod-temperature sensitive genic male sterility in wheat (Triticum aestivum L.). Acta Genetica Sinica (JGG) 31: 293-298
20. S Cao,D Liu,L Liu,X Guo, A Zhang*. (2003) Differential expression of genes related to photoperiod-temperature sensitive genic male sterility in wheat, revealed by mRNA Differential Display using G-box family primer. Acta Genetica Sinica (JGG) 30: 56-61

授权专利:

1. ScRGA-6RL.1及其编码基因与应用. 张相岐、巩彩艳、范仁春、曹双河、卫波、王献平 (专利号:ZL201410022455.3)
2. ScRGA-6RL.2及其编码基因与应用. 张相岐、巩彩艳、范仁春、曹双河、卫波、王献平 (专利号:ZL201410022567.9)
3. 鉴定小麦抽穗时间性状的方法与分子标记. 何中虎、王金平、曹双河(申请号或专利号:201610204921.9)
4. 用于鉴定小麦株高的分子标记以及特异引物. 何中虎、田秀苓、曹双河(申请号或专利号:201610347796.7)


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