Lanqin Xia

Lanqin Xia

Professor

Center for Crop Genetics and Breeding

Institute of Crop Sciences, Chinese Academy of Agricultural Sciences

No.12 Zhongguancun South Street

Beijing, 100081, China

Tel:86-10-82105804

Fax:86-10-82105804

Email:

Educations

l  1997-2000, PhD in Biochemistry and Molecular Biology, Graduate School of Chinese Academy of Agricultural Sciences, Beijing 100081, China

l  1992-1995, MS in Plant Genetics and Breeding, Graduate School of Chinese Academy of Agricultural Sciences, Beijing 100081, China

l  1984-1988, BS in Plant Nutrition and Soil Science, Shenyang Agriculture University, Shenyang, China

Working Experience

l  1/2009-now, Professor, Institute of Crop Sciences (ICS), Chinese Academy of Agricultural Sciences (CAAS)

l  01/2002-12/2008, Associate Professor, Institute of Crop Sciences (ICS), Chinese Academy of Agricultural Sciences (CAAS)

l  09/2012-12/2012, Lethbridge Research Center, Agriculture and Agri-Food, Canada, Senior Visiting Scientist.

l  08/2009-10/2009, Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Germany, Senior Visiting Scientist.

l  01/2007-6/2008, Crop Genetic Improvement Centre, Rothamsted Research, UK, Rothamsted International Research Fellow.

l  06/2005-12/2005, Crop Genetic Improvement Centre, Rothamsted Research, UK, Visiting Scientist.

l  08/2002-10/2003, Botanic Institute, Munich University, Germany, Postdoctoral Research Scientist.

l  07/2000-01/2002, Assistant Professor, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences

Research Interests

l  Exploiting novel gene editing tools and optimization through machine learning and rational design

l  CRISPR/Cas mediated genome editing in crop plants, toolkits and applications in wheat and rice improvement

l  Development of a novel generation of aphid-proof wheat plants through plant-mediated RNA interference

Academic Qualifications

l  Leading personnels of CAAS

l  Leading personnels of Ministry of Agricultural and Rural Affairs (MARA).

l  Vice President of the Chinese Society of Plant Physiology and Molecular Biology (CSPMB)

l  Vice Chairmen of the CSPMB Branch of Plant Biotechnology and Industrialization

l  Member of Branch of Genome Editing of the Chinese Society of Genetics

l  Editorial members, Journal of Integr Plant Biology (JIPB) and Journal of Integrative Agriculture (JIA),

l  Senior Editors, Frontiers in Genome Editing and aBIOTECH

Selected Publications (*corresponding authors)

1.       Yan L#, Tian J#, Li J, Li S, Zhang C, He Y, Xia LQ* (2025). Analysis of a Series of Mutants Highlights Complex Regulation of Fusarium Head Blight Resistance Conferred by Fhb1 Locus in Wheat. Plant Biotechnology Journal, DOI: 10.1111/pbi.70318. (IF: 10.5)

2.       Wang W#, Li S#, Yang J, Li J, Yan L, Zhang C, He Y, Xia LQ* (2025). Exploiting the efficient Exo:Cas12i3-5M fusions for robust single and multiplex gene editing in rice. Journal of Integrative Plant Biology, 67: 1246-1253. (IF: 9.3)

3.       Wang W#, Yan L#, Li J, Zhang C, He Y, Li S*, Xia LQ* (2024). Engineering a robust Cas12i3 variant-mediated wheat genome editing system. Plant Biotechnology Journal, 23: 860-873. (IF: 10.5)

4.       Zhang C, Zhong X, Li SY, Yan L, Li JY, He YB, Lin Y, Zhang YJ, Xia LQ* (2023). Artificial evolution of OsEPSPS through an improved dual cytosine and adenine base editor generated a novel allele conferring rice glyphosate tolerance. Journal of Integrative Plant Biology, 65(9):2194-2203. (IF: 11.4)

5.       Li JY, Zhang C, He YB, Li SY, Yan L, Yucai Li, Ziwei Zhu, Xia LQ* (2023). Plant base editing and prime editing: The current status and future perspectives, Journal of Integrative Plant Biology, 65:444-467. (IF: 11.4)

6.       Li YC#, Li SY#, Li CF, Zhang C, Yan Y, Li JY, He YB, Guo Y, Lin Y, Zhang YJ and Xia LQ* (2023). Engineering a plant A-to-K base editor with improved performance by fusion with a transactivation module. Plant Communication, 4, 100667. (IF: 10.5)

7.       Zhang JH, Li HY, Xue Zhong, Tian JF, Segers A, Xia LQ * and Frédéric Francis* (2023). Silencing an aphid-specific gene SmDSR33 for aphid control through plant-mediated RNAi in wheat. Frontiers in Plant Science, 13:1100394. (IF: 5.4)

8.       Li H#, Zhu Z#, Li S, Li J, Yan L, Zhang C, Ma Y *, Xia LQ * (2022). Multiplex precision gene editing by a surrogate prime editor in rice. Molecular Plant, 15(7): 1077–1080. (IF: 27.5)

9.       Chen JL#, Li SY#, He YB, Li JY and Xia LQ* (2022). An update on precision genome editing by HDR in plants. Plant Physiology 188: 1780-1794. (IF: 7.4)

10.    Hao ZY#, Tian JF#, Fang H#, Fang L, Xu X, …, Xia LQ*, Yuese Ning* (2022). A ubiquitin E3 ligase-VQ25-WRKY53 module fine tunes rice immunity and growth. Cell Reports 40(7), 111235. (IF: 8.8)

11.    Luo JM, Li SY, Xu JJ, Yan L, Ma YZ*, Xia LQ*. (2021). Pyramiding favorable alleles in an elite wheat variety in one generation by CRISPR/Cas9-mediated multiplex gene editing. Molecular Plant, 14: 847-850. (IF: 21.95)

12.    Li JY#, Jiao GA#, Sun YW#, Chen J#, Zhong YX, Yan L, Jiang D, Ma YZ* and Xia LQ*. (2021). Modification of starch composition, structure and properties in both winter and spring wheat varieties through CRISPR/Cas9. Plant Biotechnology Journal, 19：937-951. (IF: 13.26)

13.    Zhang JH, Zhang HT, Li SY, Li JY, Yan L, Xia LQ*. (2021). Increasing yield potential through manipulating of an ARE1 ortholog related to nitrogen use efficiency in wheat by CRISPR/Cas9. Journal of Integrative Plant Biology, 63: 1649-1663. (IF: 9.106)

14.    Xia LQ, Wang KJ, Zhu JK. (2021). The power and versatility of genome editing tools in crop improvement. Journal of Integrative Plant Biology, 63: 1591-1594. (IF: 9.106)

15.    Li SY#, Zhang C#, Li JY#, Yan L, Wang N, Xia LQ*. (2021). Present and future prospects for wheat improvement through genome editing and advanced technologies. Plant Communication, 2, 100211. (IF: 8.625)

16.    Li H, Li J, Chen J, Yan L, Xia LQ* (2020). Precise modifications of both exogenous and endogenous genes in rice by prime editing. Molecular Plant, 13: 671-674. (IF: 13.164)

17.    Li JY#, Li HY#, Chen JL, Yan L and Xia LQ* (2020). Toward precision genome editing in crop plants. Molecular Plant, 13:811-813. (IF: 13.164)

18.    Li S#, Zhang Y#, Xia LQ *, and Qi Y* (2020). CRISPR-Cas12a enables efficient biallelic gene targeting in rice. Plant Biotechnology Journal, 18: 1351-1353. (IF: 9.803)

19.    Bharat SS#, Li SY#, Li JY, Yan L, Xia LQ*. (2020). Base editing in plants: Current status and challenges. The Crop Journal, 8: 384-395. (IF: 4.407)

20.    Li SY, Li JY, He YB, Xu ML, Zhang JH, Du WM, Zhao YD* and Xia LQ * (2019). Precise gene replacement in rice by RNA transcript-templated homologous recombination. Nature Biotechnology, 37 (4): 445–450. (IF: 36.553)

21.    Sun YW#, Sparks C#, Jones HD, Riley M, Francis F, Du WM and Xia LQ* (2019). Silencing an essential gene involved in infestation and digestion in grain aphid through plant-mediated RNA interference generates aphid-resistant wheat plants. Plant Biotechnology Journal, 17: 852–854. (IF: 8.154)

22.    Li JY#, Luo JM#, Xu ML, Li SY, Zhang JH, Li HY, Yan L, Zhao YD* and Xia LQ*. (2019). Plant genome editing using xCas9 with expanded PAM compatibility. Journal of Genetics and Genomics, 46(5):277-280. (IF: 5.065)

23.    Li S#, Zhang X#, Wang W, Guo X, Wu Z, Du W, Zhao YD*, Xia LQ*. (2018). Expanding the scope of CRISPR/Cpf1-mediated genome editing in rice. Molecular Plant, 11: 995-998. (IF:10.812)

24.    Li SY#, Li JY, Zhang JH, Du WM, Fu JD, Sutar S, Yunde Zhao YD* and Xia LQ* (2018). Synthesis-dependent repair of Cpf1-induced double-strand DNA breaks enables targeted gene replacement in rice. Journal of Experimental Botany, 69(20): 4715-4721. (IF: 5.36)

25.    Li JY#, Zhang X#, Sun Y, Zhang J, Du W, Guo X, Li S, Zhao Y*, Xia LQ*. (2018). Efficient allelic replacement in rice by gene editing: a case study of the NRT1.1B gene. Journal of Integrative Plant Biology, 60(7):536-540. (IF: 3.824)

26.    Sun YW, Jiao, G., Liu, Z., Zhang, X., Li, J., Guo, X., Du, W., Du, J., Francis, F., Zhao, Y., and Xia LQ*. 2017. Generation of high-amylose rice through CRISPR/Cas9-mediated targeted mutagenesis of starch branching enzymes. Front. Plant Sci, 8, 298. (IF: 3.277)

27.    Sun YW, Zhang X, Wu C, He Y, Ma Y, Hou H, Guo X, Du W, Zhao Y, Xia LQ*. 2016. Engineering herbicide-resistant rice plants through CRISPR/Cas9-Mediated homologous recombination of acetolactate synthase. Molecular Plant, 9, 628-631. (IF: 9.326)

28.    Sun YW, Li JY, and Xia LQ*. 2016. Precise genome modification via sequence-specific nucleases-mediated gene targeting for crop improvement. Front. Plant Sci, 7: 1928. (IF: 4.298)